Advancements in Pediatric Dermatology Research

Advancements in Pediatric Dermatology Research

Part of being an excellent dermatologist is staying up to date with the latest trends in this medical specialty. This ensures our patients can receive the most effective course of action. At Santa Monica Dermatology Group, serving Santa Monica, CA, and the nearby region, our practitioners strive to give patients the latest options. Below are some of the most recent pediatric dermatology treatments available.

Methotrexate

Methotrexate is a common treatment for rheumatoid arthritis and has been used to treat certain types of cancer. Researchers have recently found it may have a positive impact on juvenile atopic dermatitis patients. This powerful drug is recommended for severe cases only, such as conditions that interfere with a child's quality of life.

Dupilumab

This product hit the market for kids ages 12-17 with atopic dermatitis in 2019 and later became available to patients as young as six months old. It goes by the name-brand Dupixent and is also useful for asthma, chronic rhinosinusitis, and more. In pediatric patients with moderate to severe atopic dermatitis, the drug gets to the root of the eczema -- inflammation -- by stopping the immune system from preventing interleukins from binding to cell surface receptors. Pediatric dermatologists, including the Santa Monica Dermatology Group, serving Santa Monica, CA, are impressed by how well it targets inflammation.

Tralokinumab

In 2023, tralokinumab, which also goes by the brand Adbry, received the U.S. Food and Drug Administration's approval for children ages 12-17 with moderate to severe atopic dermatitis. It's the first biologic on the market that binds to interleukin-13 cytokine. Once it binds, it interferes with the cytokine's ability to interact with its receptors. In turn, it reduces inflammation.

In studies, 21 percent of patients received a 0 or 1 on the Investigator's Global Assessment scale, which means there was no to little presence of the skin condition after treatment.

IDP-126 Topical Gel

IDP-126 is a combination of clindamycin, adapalene, and benzoyl peroxide and is for treating acne. This particular gel is sold under the name CABTREO. Currently, the FDA has approved it for acne in children ages 12 and up. The results showed half of the patients received success by week 12, while 72-80 percent saw relief from either inflammatory or non-inflammatory lesions. As a result, this is an option for pediatric dermatology patients in Santa Monica, CA. Call our office at (310) 829-4484.


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